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Biblioteca (s) : |
INIA La Estanzuela; INIA Las Brujas; INIA Tacuarembó; INIA Treinta y Tres. |
Fecha : |
21/02/2014 |
Actualizado : |
30/10/2019 |
Tipo de producción científica : |
Artículos en Revistas Agropecuarias |
Autor : |
QUINTANS, G. |
Afiliación : |
GRACIELA QUINTANS ILARIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
Título : |
IV Taller de evaluación de diagnósticos de gestación en ganado de carne |
Fecha de publicación : |
2006 |
Fuente / Imprenta : |
Revista INIA, 2006, no. 7, p. 9-11 |
ISSN : |
1510-9011 |
Idioma : |
Español |
Thesagro : |
BOVINOS; DIAGNOSTICO; GANADO DE CARNE; GESTACION; PRODUCCION ANIMAL; REPRODUCCIÓN; URUGUAY. |
Asunto categoría : |
-- L53 Fisiología Animal - Reproducción |
URL : |
http://www.ainfo.inia.uy/digital/bitstream/item/810/1/111219220807162608.pdf
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Marc : |
LEADER 00538naa a2200205 a 4500 001 1012959 005 2019-10-30 008 2006 bl uuuu u00u1 u #d 022 $a1510-9011 100 1 $aQUINTANS, G. 245 $aIV Taller de evaluación de diagnósticos de gestación en ganado de carne 260 $c2006 650 $aBOVINOS 650 $aDIAGNOSTICO 650 $aGANADO DE CARNE 650 $aGESTACION 650 $aPRODUCCION ANIMAL 650 $aREPRODUCCIÓN 650 $aURUGUAY 773 $tRevista INIA, 2006, no. 7, p. 9-11
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Registro original : |
INIA Las Brujas (LB) |
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Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
27/01/2020 |
Actualizado : |
27/01/2020 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
ESCRIBANO, C.; SARAVIA, A.; COSTA, M.; CASTELLS, D.; CIAPPESONI, G.; RIET-CORREA, F.; FREIRE, T. |
Afiliación : |
CECILIA ESCRIBANO, Grupo de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay; INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANDERSON SARAVIA DE MELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MONIQUE COSTA, Grupo de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay; DANIEL CASTELLS, Secretariado Uruguayo de Lana, Florida, Uruguay; CARLOS GABRIEL CIAPPESONI SCARONE, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; TERESA FREIRE, Grupo de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay. |
Título : |
Resistance to Haemonchus contortus in Corriedale sheep is associated to high parasite-specific IgA titer and a systemic Th2 immune response. |
Fecha de publicación : |
2019 |
Fuente / Imprenta : |
Scientific Reports, 1 December 2019, Volume 9, Issue 1, Article number 19579. OPEN ACCESS. Doi: https://doi.org/10.1038/s41598-019-55447-6 |
ISSN : |
2045-2322 |
DOI : |
10.1038/s41598-019-55447-6 |
Idioma : |
Inglés |
Notas : |
Article history: Received: 21 June 2019 / Accepted: 27 November 2019 / Published: 20 December 2019.
Funding information:
We acknowledge the personnel from Uruguayan Wool Secretariat that assisted with animal studies. This project was funded by INIA (Uruguay) and CSIC-VUSP (Uruguay). C.E. was funded by a scholarship by INIA. |
Contenido : |
ABSTRACT.
Gastrointestinal nematode infections, including Haemonchus contortus, are one of the main causes of economic losses to ovine farmers worldwide. In order to contribute to the control of nematode infections and avoid parasite spreading we generated divergent resistant and susceptible sheep breeds and evaluated the adaptive immunity of these animals developed upon experimental infection against H. contortus. The selection of resistant or susceptible animals from the Corriedale Breed has been based on Expected Progeny Differences for faecal egg counts per gram. Furthermore, animals from the resistant Corriedale line were inseminated with imported semen from Australian Rylington Merino rams. Thus, the objective of this work was to analyze the adaptive immune response in both susceptible and resistant obtained lambs. Our results indicate that there is a potent parasite-specific local and systemic immune response in resistant animals and that although susceptible lambs can produce high levels of IgA antibodies during the infection, their antibody response is delayed which, together with an impaired specific-Th2 response, does not contribute to initial parasite elimination. Our results shed light into the immune mechanisms that mediate resistance to H. contortus and could constitute important assets to sheep farmers, not only as a means to detect resistance, but also to enhance the efficiency of selection in stud flocks.
© 2019, The Author(s). |
Palabras claves : |
HAEMONCHUS; SHEEP. |
Asunto categoría : |
L01 Ganadería |
URL : |
https://www.nature.com/articles/s41598-019-55447-6.pdf
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Marc : |
LEADER 02635naa a2200253 a 4500 001 1060699 005 2020-01-27 008 2019 bl uuuu u00u1 u #d 022 $a2045-2322 024 7 $a10.1038/s41598-019-55447-6$2DOI 100 1 $aESCRIBANO, C. 245 $aResistance to Haemonchus contortus in Corriedale sheep is associated to high parasite-specific IgA titer and a systemic Th2 immune response.$h[electronic resource] 260 $c2019 500 $aArticle history: Received: 21 June 2019 / Accepted: 27 November 2019 / Published: 20 December 2019. Funding information: We acknowledge the personnel from Uruguayan Wool Secretariat that assisted with animal studies. This project was funded by INIA (Uruguay) and CSIC-VUSP (Uruguay). C.E. was funded by a scholarship by INIA. 520 $aABSTRACT. Gastrointestinal nematode infections, including Haemonchus contortus, are one of the main causes of economic losses to ovine farmers worldwide. In order to contribute to the control of nematode infections and avoid parasite spreading we generated divergent resistant and susceptible sheep breeds and evaluated the adaptive immunity of these animals developed upon experimental infection against H. contortus. The selection of resistant or susceptible animals from the Corriedale Breed has been based on Expected Progeny Differences for faecal egg counts per gram. Furthermore, animals from the resistant Corriedale line were inseminated with imported semen from Australian Rylington Merino rams. Thus, the objective of this work was to analyze the adaptive immune response in both susceptible and resistant obtained lambs. Our results indicate that there is a potent parasite-specific local and systemic immune response in resistant animals and that although susceptible lambs can produce high levels of IgA antibodies during the infection, their antibody response is delayed which, together with an impaired specific-Th2 response, does not contribute to initial parasite elimination. Our results shed light into the immune mechanisms that mediate resistance to H. contortus and could constitute important assets to sheep farmers, not only as a means to detect resistance, but also to enhance the efficiency of selection in stud flocks. © 2019, The Author(s). 653 $aHAEMONCHUS 653 $aSHEEP 700 1 $aSARAVIA, A. 700 1 $aCOSTA, M. 700 1 $aCASTELLS, D. 700 1 $aCIAPPESONI, G. 700 1 $aRIET-CORREA, F. 700 1 $aFREIRE, T. 773 $tScientific Reports, 1 December 2019, Volume 9, Issue 1, Article number 19579. OPEN ACCESS. Doi: https://doi.org/10.1038/s41598-019-55447-6
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